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Question

The preferred respiratory substrate is

A
Glucose.
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B
Fats.
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C
Proteins.
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D
Polypeptide.
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Solution

The correct option is A Glucose.
In all organisms, glucose is the favoured substrate for respiration. All carbohydrates are usually first converted into glucose before they are used for respiration. Other substrates can also be respired, but then they do not enter the respiratory pathway at the first step i.e., glycolysis. Fats would need to be broken down into glycerol and fatty acids first. If fatty acids were to be respired they would first be degraded to acetyl CoA and enter the pathway. Glycerol would enter the pathway after being converted to phosphoglyceraldehyde (PGAL). The proteins would be degraded by proteases and the individual amino acids (after deamination) depending on their structure would enter the pathway at some stage within the Krebs cycle or even as pyruvate or acetyl CoA.

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