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Question

The probability of the male child of a haemophilic father and a normal mother becoming haemophilic is

A
25%
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B
0%
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C
50%
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D
100%
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Solution

The correct option is B 0%
Haemophilia is an X-linked recessive disorder. Since father transmits its X chromosome to the daughters, not to son, so the haemophilic father would not affect the disease inheritance of his son. Son receives its X chromosome from mother which means that the mother should have at least one copy of affected allele to transmit the disease to her son. Mother with both normal copies of X-chromosome will have all normal sons.
So, the correct answer is option B.

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