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Question

The problem of erythroblastosis foetalis occurs when

A
Both father and mother are Rh positive
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B
Both father and mother are Rh negative
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C
Mother is Rh positive and father is Rh negative
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D
Father is Rh positive and mother is Rh negative
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Solution

The correct option is D Father is Rh positive and mother is Rh negative
If a woman who is Rh- negative married to a man who is Rh- positive produces a baby may have Rh- positive blood, inherited from the father. Rh antibodies are harmless until the mother's second or later pregnancies. If she is ever carrying another Rh- positive child, her Rh antibodies will recognize the Rh proteins on the surface of the baby's blood cells as foreign and attack those cells. This can lead to rupture of the baby's RBCs known as haemolytic or Rh disease of the newborn or erythroblastosis foetalis.
Therefore, the correct answer is option D.

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