Question

The proper sequence of stages in glycolysis is

• A. Glucose priming, cleavage and rearrangement, oxidation, ATP generation
• B. Cleavage and rearrangement, glucose priming, ATP generation, oxidation
• C. Glucose priming, oxidation, cleavage and rearrangement, ATP generation
• D. ATP generation, oxidation, glucose priming, cleavage and rearrangement

Answer 1

The correct option is A

Glucose priming, cleavage and rearrangement, oxidation, ATP generation

Glycolysis is a ten step process. In the first few steps glucose is primed. It is converted to glucose-6-phosphate, which is trapped in the cell and can not leave the cell due to its negative charge. It is then broken down and rearranged to form two high energy 3C molecules of glyceraldehyde-3-phosphate. Glyceraldehyde-3-phosphate then undergoes oxidation to form 1,3-bisphophoglycerate, creating a high energy NADH molecule. The last aspect of glycolysis is the harvest phase, where the ATPs invested in the priming are returned and 2 more is generated as a pay off.