Question

The ratio of enzyme to substrate molecules can be as high as

• A. $1:100,000$
• B. $1:50,000$
• C. $1:10,000$
• D. $1:1,000$

Answer 1

Answer: (A)

$1:100,000$

The enzyme attaches to the active site of the substrate. On attachment to the active site, the substrate is changed into the product. The active site has a residue which helps in the attachment of substrate. The substrate molecules form a temporary bond with the enzyme at the active site. The ratio of enzyme to substrate molecules can be as high as 1 : 100,000. If the amount of substrate increases more than this, it will not get the vacant active site for attachment which terminates the reaction.

So, the correct answer is option A.