Question

The reaction $C_6{H}_{5}N{H}_2+CHC{l}_3+3KOH\to C_6{H}_{5}NC+3KCl+3H_{2}O$ is known as

• A. Carbylamine reaction
• B. Reimer-Tiemann reaction
• C. Kolbe reaction
• D. Hofmann's degradation

Answer 1

The correct option is A Carbylamine reaction

Carbylamine reaction mechanism includes the addition of amine to the intermediate created from the dehydrohalogenation of chloroform. This intermediate is called dichlorocarbene. The carbylamine reaction is also known as Hoffmann isocyanide synthesis. It is the reaction of a primary amine, chloroform and a base to synthesize isocyanides. The dichlorocarbene intermediate is very important for this conversion. The carbylamine reaction cannot be used to synthesize isocyanides from secondary or tertiary amines.

This is Carbylamine reaction which is used to detect primary amines. The product formed is isocyanide which has foul smelling and can be easily detected. Secondary and tertiary amines dont give this reaction.

The reaction is as follows:
$RN{H}_2+CHC{l}_3+3KOH\to RNC+3KCl++3H_{2}O$

Hence, (a) is the correct option.