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Question

The site of production of ADA in the body is:

A
Osteocytes
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B
Blood plasma
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C
Erythrocytes
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D
Lymphocytes
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Solution

The correct option is D Lymphocytes
Adenosine deaminase enzyme:
Adenosine deaminase enzyme
  • ADA enzyme is synthesised in lymphocytes, which helps in the proliferation of T lymphocytes.
  • It converts adenosine to inosine. This step is involved in the metabolism of nucleotides and helps in the recycling of nucleotides.
  • This enzyme plays an important role in providing immunity.
  • When ADA enzyme producing gene is absent, the cDNA of ADAgene is incorporated into lymphocytes using a retroviral vector and these lymphocytes are injected into the body which produce ADAenzyme.

Final answer:lymphocytes

Summary:
Adenosine deaminase enzyme (ADA)
Adenosine deaminase enzyme (ADA) is synthesised in lymphocytes, helps in proliferation of T lymphocytes.

Final answer: Lymphocytes

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