The correct option is A biopsy
Biopsy is a medical test involving the extraction of sample cells or tissues for examination to determine the presence or extent of a disease. It is the most common way to identify cancer.
Depending upon the location of the tissue, procedures for a biopsy can vary. For example if a dermatologist suspects skin cancer in a patient, the affected area is usually accessible and it is relatively easy to take out a tissue sample from skin. But if a patient has a stomach tumour, the procedure to obtain a biopsy can be a bit more complex.
CT scan, MRI and X ray are all forms of imaging.