The technique used to determine the abnormalities in number and structure of chromosomes is

Karyogram

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Metacentric analysis

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Karyotype analysis

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Karyokinesis

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Solution

The correct option is C Karyotype analysis
Chromosome analysis or karyotyping is a test that evaluates the number and structure of a person's chromosomes in order to detect abnormalities. Chromosomes are thread-like structures within each cell nucleus and contain the body's genetic blueprint.

So, the correct answer is 'Karyotype analysis'.

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