Question

The total number of amines among the following which can be synthesized by Gabriel synthesis is

• A.

  

• B. ${\mathrm{CH}}_3{\mathrm{CH}}_2{\mathrm{NH}}_2$
• C.

  

• D.

  

Answer 1

The correct option is C

Explanation for the correct option:

C:

Gabriel Synthesis:

• By reacting with alkyl halides, potassium phthalimide, a $-{\mathrm{NH}}_2$synthon, enables the creation of primary amines.
• The phthalimide is no longer a nucleophile and does not react after alkylation.
• A stable cyclic product is produced when the product is cleaved through a reaction with a base or hydrazine.
• And only $1^{\mathrm{o}}$ amines can be prepared by Gabriel Synthesis.

Explanation for the incorrect answer:

• Options A, B and D are not following the Gabriel synthesis.

Therefore, Option C is the correct option.