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Quaternary Structure of Protein

The union of ...

Question

The union of several polypeptide chains to form a complete protein is regarded at what level of protein structure?

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Solution

The union of several polypeptide chains to form a complete protein is regarded at quaternary level of protein structure.

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Q. What structural level of protein involves the coiling of a single polypeptide chain stabilised by H-bonds?

In which structure of protein, the polypeptide chain forms all possible hydrogen bonds by twisting into right handed screw?

Q. Myoglobin is a heme-containing protein composed of a single polypeptide chain. It is capable of binding oxygen to its heme group. Hemoglobin is a heme-containing protein composed of four polypeptide chains, each chain being capable of binding oxygen to its own heme group.
Structural analysis has revealed the structure of the myoglobin protein to be nearly identical to the structure of the individual polypeptide chains of hemoglobin.
Scientists have compared the primary structure of both myoglobin and hemoglobin proteins from humans to those of other species as a way of tracing evolutionary relatedness. Examine the data table below.

Protein Sequence Differences Between Human and Other Species

	Myoglobin	Hemoglobin
Whales	25	17
Lampreys	64	125
Sharks	88	-
Horseshoe Crabs	-	-

Base on the data table and the information provided regarding the structures of the two molecules, which of the following statements is correct?

Q. Regular folding of the backbone of the polypeptide chain in the secondary structure of proteins arises due to:

Q. How many polypeptide chains are present in an multimeric protein ?

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Quaternary Structure of Protein

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