The correct option is
A pH 4 to pH 10
The maximum effectiveness of pineapple is approximately 10. 50% of that is 5. The pH range where pineapple extract operates at least 5 or better is pH 4 to pH 10. The change in pH may not only affect the shape of an enzyme but it may also change the shape or charge properties of the substrate so that either the substrate cannot bind to the active site or it cannot undergo catalysis. In general, the enzyme has an optimum pH. However, the optimum pH is not the same for each enzyme.
Therefore, the correct answer is option A.