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Question

There are 64 types of codons in genetic code dictionary because


A
There are 64 types of tRNA's found in cell.
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B
There are 44 meaningless and 20 codons for amino acids.
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C
There are 64 amino acids for coding.
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D
Genetic code is triplet.
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Solution

The correct option is D Genetic code is triplet.
The genetic code is a triplet and this triplet nature can be explained as:
  • There are four nitrogenous bases (Adenine, Guanine, Thymine and Cytosine) and these four bases code for 20 amino acids.
  • If genetic code is a doublet then a combination of two nitrogenous bases will give 4 x 4 = 16 codons, which is insufficient for 20 amino acids.
  • George Gamow in 1954 explained the possibility of three letter code i.e. triplet codon. This will give 4 x 4 x 4 = 64 codons, which is more than enough to code for twenty amino acids.
Hence, the genetic code is a triplet.
So, the correct answer is 'Genetic code is triplet'.

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