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Question

There are three genes a, b and c. The percentage of crossing over between a and b is 20%, b and c is 28% and a and c is 8%. What is the sequence of genes on chromosomes?

A
b, a, c
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B
a, b, c
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C
a, c, b
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D
None
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Solution

The correct option is A b, a, c

Linkage/ Cross over/ Chromosome maps is a graphic representation of relative positions/ order and relative distances of genes in a chromosome in the form of a line like a linear road map depicting different places and their relative distances without giving exact mileage.
It is based on Morgan’s hypothesis (1911), which states that frequency of crossing over/recombination between two linked genes is directly proportional to the physical distance between the two.
1 map unit or centimorgan is equivalent 1% recombination between two genes.
Percentage of crossing over between a and b is 20% so they are 20 map distance apart and b and c are 28 map distance apart.
Therefore the correct sequence of genes in the chromosome is
b - 20 - a - 8 - c


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