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Question

Three copies of chromosome – 21 in a child with down’s syndrome have been analysed using molecular biology technology to detect any possible DNA polymorphism with reference to different alleles located on chromosome – 21. Results showed that out of 3 copies 2 of the chromosomes of the child contain the same alleles as one of the mother’s alleles. Based on this, when did the non – disjunction event most likely occur?


A

Maternal meiosis – I

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B

Maternal meiosis –II

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C

Paternal meiosis – I

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D

Paternal meiosis – II

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