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Three Mark Questions:
Haemophilia is sex-linked recessive disorder of humans. The pedigree chart given below shows the inheritance of haemophilia in one family. Study the pattern of inheritance and answer the questions given (a) Give all the possible genotypes of the members 4, 5 and 6 in the pedigree chart
(b) A blood test shows that the individual 14 is a carrier of haemophilia. The member numbered 15 has recently married numbered 14. What is the probability that their first child will be haemophilic male.
Haemophilia is sex-linked recessive disorder of humans. The pedigree chart given below shows the inheritance of haemophilia in one family. Study the pattern of inheritance and answer the questions given (a) Give all the possible genotypes of the members 4, 5 and 6 in the pedigree chart
(b) A blood test shows that the individual 14 is a carrier of haemophilia. The member numbered 15 has recently married numbered 14. What is the probability that their first child will be haemophilic male.
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Solution
Let the dominant allele be 'A' and let the recessive allele be 'a'.(a) Member 4 could be Aa (carrier) or aa (unaffected). - Member 5 is aa (affected).
Member 6 could be Aa (carrier) or aa (unaffected). (b) Member 14 is a carrier female which means the genotype is Aa. Member 15 is an unaffected male (AA). So, the probability that the first child is a haemophilic male is 1/4.
(a) Member 4 could be Aa (carrier) or aa (unaffected).
- Member 5 is aa (affected).
Member 6 could be Aa (carrier) or aa (unaffected).
(b) Member 14 is a carrier female which means the genotype is Aa. Member 15 is an unaffected male (AA). So, the probability that the first child is a haemophilic male is 1/4.
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