Question

Three Mark Questions :
Why are human females rarely haemophilic? Explain. How do haemophilic patients suffer?

Answer 1

Haemophilia is a X linked recessive disorder. In human females both the allosomes are X chromosomes, so for haemophilia to be seen in females both the X chromosomes need to be affected. If only one X chromosome is affected then she will be a carrier of the disease as she will be able to pass it to the future generations but will not show the symptoms of the disease. In patients having haemophilia, the blood clotting factors are absent. Due to this, blood does not clot easily on injury. As a result bruising is seen and increased bleeding in joints may occur due to which there is joint pain and swelling.