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Question

Threshold potential is a state of depolarisation at which _____.


A

An action potential is sure to fire

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B

Voltage gated Na+ channels open

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C

Membrane potential is near -55mV

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D

All of the above

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Solution

The correct option is D

All of the above


Threshold potential can be defined as the state of depolarisation at which an action potential is sure to fire. When a neuronal membrane depolarizes to about -55mV, the voltage gated Na+ channels open. Once these channels open there is no preventing an action potential because these channels, regulated by voltage open causing a positive cascade i.e. opening of these channels depolarises the membrane further by allowing Na+ ions inside the cell and more depolarisation opens more voltage gated sodium channels.


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