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Question
To balance the bicarbonate ion loss from RBC, the chloride ions move into RBC; it is known as
To balance the bicarbonate ion loss from RBC, the chloride ions move into RBC; it is known as
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Solution
The correct option is D Both A and B
Red blood cell membranes are impermeable to hydrogen ions but are able to exchange bicarbonate ions for chloride ions. A rise in intracellular bicarbonate causes chloride intake and bicarbonate export. The term chloride shift refers to this exchange. As a result, blood chloride concentration is lower in systemic venous blood than in systemic arterial blood or in pulmonary circulation because the levels of CO2 and therefore bicarbonate are higher in systemic venous blood, providing less of a driving force for exchange.
Red blood cell membranes are impermeable to hydrogen ions but are able to exchange bicarbonate ions for chloride ions. A rise in intracellular bicarbonate causes chloride intake and bicarbonate export. The term chloride shift refers to this exchange. As a result, blood chloride concentration is lower in systemic venous blood than in systemic arterial blood or in pulmonary circulation because the levels of CO2 and therefore bicarbonate are higher in systemic venous blood, providing less of a driving force for exchange.
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