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Question

To describe transforming principle, Frederick Griffith performed series of experiments by selecting two strains of Streptococcus pneumoniae namely S-strain (virulent) and R-strain (non-virulent).
Which of the following steps does not describe this experiment?
[0.7 mark]

A
S-strain live Injected into mice−−−−−−−−−−Mice die
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B
S-strain (heat-killed) + R-strain (live)Injected into mice−−−−−−−−−−Mice die
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C
R-strain (heat-killed) + S-strain (live)Injected into mice−−−−−−−−−−Mice live
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D
S-strain (heat-killed)Injected into mice−−−−−−−−−−Mice live
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Solution

The correct option is C R-strain (heat-killed) + S-strain (live)Injected into mice−−−−−−−−−−Mice live
When the mixture of S-strain (heat-killed) and R-strain (live) of Streptococcus pneumoniae bacteria was injected to the mice, the mice died. It was due to the transformation of R-strain by heat-killed S-strain bacteria.

Injection of R-strain (heat-killed) and S-strain (live) into the mice caused the mice died due to virulent live S-strain.

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