Question

To treat myasthenia gravis,

• A. Acetylcholine esterase activity is inhibited
• B. Receptors on motor end plate are reduced
• C. Secretion from nerve terminals is reduced
• D. Secretion from nerve terminals is enhanced

Answer 1

Answer: (A)

Acetylcholine esterase activity is inhibited

Myasthenia gravis is a disease caused due to the antibodies produced by an immune system that blocks or destroy the receptor sites for a neurotransmitter called acetylcholine. The enzyme esterase or acetylcholine esterase break the acetylcholine and deactivates the neurotransmitter to stop muscle activation.

During treatment of myasthenia gravis, it is prevented by using a chemical drug acetylcholinesterase inhibitor. These acetylcholinesterase inhibitors increase the amount of acetylcholine available and so help muscle activation and contraction.

So the correct option is 'Esterase activity is inhibited'.