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Question

To which of the following disease, this pedigree analysis can not belong

A
Colour blindness
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B
Huntington's disease
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C
Polycystic kidney
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D
Neurofibromatosis
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Solution

The correct option is A Colour blindness
In the pedigree, an affected male gives rise to affected son and daugter, so, the inheritance is not sex-limked. If the trait was recessive, mother should be a carrier. Since pedigree doesnt say the mother to be acrrier, we can safely assume it is an autosomal dominant disease.
Colour blindness is an X - linked recessive and all other options are autosomal dominant disorders.

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