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DNA

Transformatio...

Question

Transformation experiment was conducted by

A

Griffith

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B

Linus Pauling

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C

Messelson and Stahl

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D

Watson and Crick

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Solution

The correct option is A Griffith
Matthew Meselson and Franklin Stahl conducted an experiment in 1958 which supported the hypothesis that DNA replication was semiconservative. Griffith's experiment by Frederick Griffith, was the first experiment suggesting that bacteria are capable of transferring genetic information through a process known as transformation. Linus Pauling work comprised on the structure of DNA. This included the structure of the most important chain - the alpha helix chain. Watson and Crick described the structure of the DNA.

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Q. Choose the correct answer from the alternatives given :
Watson and Crick (1953) proposed DNA double helix model and won the Nobel Prize; their model of DNA was based on
(i) X-ray diffraction studies of DNA done by Wilkins and Franklin
(ii) Chargaffs base equivalence rule
(iii) Griffiths transformation experiment
(iv) Meselson and Stahls experiment.

Q. The plasmid used by Cohen and Boyer for the first transformation experiment was

Q. Explain transformation experiments conducted by Fredric Griffth. Add note biochemical characterization of transforming principle.

Q. [5]
(a) State the 'Central dogma' as proposed by Francis Crick. Are there any exceptions to it? Support your answer with a reason and an example.

(b) Explain how the biochemical characterisation (nature) of 'Transforming Principle' was determined, which was not defined from Griffith's experiments.

Q. [5]
(a) State the 'Central dogma' as proposed by Francis Crick. Are there any exceptions to it? Support your answer with a reason and an example.

(b) Explain how the biochemical characterisation (nature) of 'Transforming Principle' was determined, which was not defined from Griffith's experiments.

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