Question

Transformation experiment was performed on which of the following bacteria?

• A. E. coli
• B. Salmonella
• C. Pasteurella pestis
• D. Diplococcus pneumoniae

Answer 1

Answer: (D)

Diplococcus pneumoniae

Griffith did transformation experiment in which he used two strains of Pneumococcal bacteria: ||-R and |||-S. |||-S had polysaccharide capsule and was resistant to host immune system and can kill host while ||-R did not have a capsule and was not able to kill the host. In his experiment, he killed |||-S strain and added their remains to ||-R. None of them was able to kill the host alone but the combination was able. He concluded that type ||-R had been transformed into type |||-S by 'Transforming Principle' that was part of dead |||-S strain.