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Question

Transgenic mice may be used for testing of ________________.


A

The safety of vaccines

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B

Efficiency of fertilisers

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C

Dose of antibiotics

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D

All the above

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Solution

The correct option is A

The safety of vaccines


The correct option is Option A.

Explanation for the correct option:

  1. Transgenic animals are those that have had their genomes altered.
  2. The transgene is the foreign gene that is inserted.
  3. To change the animal's DNA, a foreign gene is put into its genome.

Use of transgenic animals:

  1. Most often, such animals are generated by microinjecting DNA into the pronuclei of a fertilized egg, which is then implanted into the oviduct of a pseudopregnant surrogate mother.
  2. As a result, the receiving animal produces genetically changed offspring.
  3. This procedure is used to improve the target animal's genetic features.
  4. They are employed as model organisms to assess vaccine safety before they are administered to people.
  5. Transgenic mice are being created to test vaccination protection before it is used on people.
  6. These mice are used to assess the effectiveness of polio vaccinations.

Explanation for the incorrect options:

Option B:

  1. Fertilizer efficiency is always achieved by direct application to the fields.
  2. As a result, this is the erroneous option.

Option C:

  1. Antibiotic dosages are not evaluated using transgenic mice.
  2. As a result, this is the erroneous option.

Final Answer: Transgenic mice may be used for testing of the safety of vaccines.


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