Question

The transition state structure of the substrate formed during an enzymatic reaction is:

• A. permanent but unstable
• B. transient but stable
• C. permanent and stable
• D. transient and unstable

Answer 1

The correct option is D

transient and unstable

The correct option is D:

Explanation of the correct option:

1. The transition state corresponds to the highest energy.
2. The transition state is the state where the intermediate products have the highest level of energy.
3. Compared to the energy of substrate or product, the transition state has more free energy.
4. Due to this free energy, the transition state is unstable and temporary i.e., transient.

Final answer: The transition state structure of the substrate formed during an enzymatic reaction is transient and unstable.