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Question

Transition state structure of the substrate formed during an enzyme reaction is

A
Permanent and stable
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B
Transient but stable
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C
Permanent but unstable
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D
Transient and unstable
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Solution

The correct option is D Transient and unstable
Transition state is the state of an activated complex which is highly unstable and readily changes into the product. Enzymes are proteins which accelerate the rate of the reaction. The substrate and product have different energy state. The energy gap between the substrate and the product is known as activation energy which is the minimum energy required to initiate a reaction. The enzymes lower the activation energy and lead to the formation of activated complex, which is also known as transition state and finally changes to the product.
So, the correct answer is option D.

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