Question

Transplantation of tissues/organs often fails due to non-acceptance by the patient’s body. Which type of immune response is responsible for such rejections?

Answer 1

Rejection of transplant

• Transplantation of tissues or organs faces the risk of rejection as it is recognised by the immune cells as non-self.
• The cell-mediated immune response mainly involves T cells which release cytokines in response to foreign objects (non-self cells).
• T cells and antibodies damage the organ, and may cause reduced organ function or organ failure.

Final answer
a. Cell-mediated immune response