Question

Trypsinogen is an inactive enzyme secreted by the pancreas. It is activated by

• A. Pepsin of stomach
• B. Chymotrypsin
• C. Bile
• D. Enterokinase

Answer 1

Answer: (D)

Enterokinase

Pancreatic juice is composed of various digestive enzymes like trypsinogen, chymotrypsinogen, elastase, carboxypeptidase, pancreatic lipase, nucleases and amylase. These enzymes help in further breakdown of carbohydrates, proteins and fats.

Trypsinogen is a precursor form of trypsin. Trypsin is involved in breakdown of proteins. It cleaves the peptide bond of basic amino acids. The inactivated form trypsinogen is activated by enteropeptidase. It is also called as enterokinase. Enterokinase is produced by the duodenum and is found in the intestinal mucosa. It converts trypsinogen to trypsin.

Chymotrypsin is an enzyme which cleaves the peptide bond along with trypsin.

Pepsin is an enzyme which breaks down proteins into smaller peptides.

Bile is involved in the digestion of lipids.

Thus, the correct answer is option D.