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Question

Tumor cells have been shown to avoid detection and destruction by the immune system. Therefore, the patients are given certain substances called biological response modifiers (BRM) which activates their immune system and helps in destroying the tumor. Identify the BRM:

A
Alpha lactalbumin
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B
Alpha interferon
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C
Alpha-1 antitrypsin
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D
Gamma globulin
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Solution

The correct option is B Alpha interferon
BRM is a type of treatment that uses substances made from living organisms to treat disease. These substances may occur naturally in the body or may be made in the laboratory.

Cancer cells are recognised as self cells by the hosts immune system and are therefore not attacked. These BRMs attach to the cancer cells and then the immune cells can identify them as non self and can destroy them.

Two BRMs that are used in cancer immunotherapy are:
  • Interleukin-2 (IL-2)
  • Alpha interferon (IFN)
Therefore the correct answer is alpha interferon.

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