Since cards are drawn without replacement.
Total no. of cases, i.e., P(S)=51×51=2652
Let A be the event of getting a queen and king of opposite colours
A={QhKs,QhKc,QdKs,QdKc,QsKh,QsKd,QcKh,QcKd,KhQs,KhQc,KdQs,KdQc,KsQh,KsQd,KcQh,KcQd}
Here h,s,d,c represent heart, spade, diamond and club respectively.
∴n(A)=16
∴P(A)=n(A)n(S)=162652=4663
Hence the probability that one of these is a queen and the other is a king of opposite colour is 4663.