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Question
Unwinding of DNA is done by
Unwinding of DNA is done by
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Solution
The correct option is C Helicase
Helicases move along the double-stranded DNA and separate the strands by breaking hydrogen bonds at the expense of energy from ATP. DNA unwinding by helicases creates topological stress in the helical DNA structure which is relieved by the action of topoisomerases. These enzymes transiently break both DNA strands of one chromosome thereby, making the other chromosome pass through the break and relieve the stress. Ligase enzyme joins two large molecules by forming a new chemical bond; for example, DNA ligase joins two DNA fragments together via phosphodiester bond between two nucleotides. Exonucleases enzymes remove nucleotides one at a time from the end of a polynucleotide chain. They shorten the DNA by one nucleotide at a time, they do not digest it into fragments. The correct answer is C.
Helicases move along the double-stranded DNA and separate the strands by breaking hydrogen bonds at the expense of energy from ATP. DNA unwinding by helicases creates topological stress in the helical DNA structure which is relieved by the action of topoisomerases. These enzymes transiently break both DNA strands of one chromosome thereby, making the other chromosome pass through the break and relieve the stress.
Ligase enzyme joins two large molecules by forming a new chemical bond; for example, DNA ligase joins two DNA fragments together via phosphodiester bond between two nucleotides.
Exonucleases enzymes remove nucleotides one at a time from the end of a polynucleotide chain. They shorten the DNA by one nucleotide at a time, they do not digest it into fragments. The correct answer is C.
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