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Countercurrent Multiplication

Value based q...

Question

Value based questions.
If a person who has had a heart transplant receives prednisone (a glucocorticoid) to help prevent rejection of the transplanted tissue, will blood levels of ACTH and CRH (corticotropin releasing hormone) be high or low and why ?

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Solution

By external administration of prednisone, there will be negative feedback on the release of ACTH and CRH hence their concentrations in the blood will be low.

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