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Question

Watson and Crick's 3-dimensional DNA model was based upon the findings of
A. Meselson and Stahl
B. Erwin Chargaff
C. Hershey and Chase
D. Wilkins and Franklin

Choose the correct option

A
A and B
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B
C and D
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C
A and C
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D
B and D
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Solution

The correct option is D B and D
Watson and Crick’s 3-dimensional DNA model was based upon the X-ray diffraction data of DNA obtained by Rosalind Franklin and Maurice Wilkins and base paring rules given by Erwin Chargaff.

X-Ray diffraction image and a model of DNA

The 𝝰-helix structure of protein discovered by Linus Pauling gave an idea to Watson and Crick, to ideate how bases in DNA could be arranged. They used the Chargaff's rule and DNA X-ray diffraction data to make a 3-D model of DNA which is a double-stranded helix.
Meselson and Stahl proved the semi-conservative nature of DNA replication.
Hershey and Chase proved that DNA is the genetic material with the help of transduction experiments.

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