A plucked guitar string releases sound energy. The music we hear is the result of the string returning to its equilibrium position. The movement of an oscillating body is called harmonic motion. If you were to graph the position, velocity, or acceleration of an oscillating body against time, the result would be a sinusoidal wave. The vibration of a source sets the amplitude of a wave. It transmits energy into the medium through its vibration. More energetic vibration corresponds to larger amplitude. The molecules move back and forth more vigorously.
Hence, when the string is plucked in the middle with a force of greater magnitude, the loudness of the sound is higher.