A mutation is a change in the nucleic acid sequence of an organism's genome, virus, or extrachromosomal DNA in biology.
DNA or RNA can be found in viral genomes.
Errors in DNA or viral replication, mitosis, meiosis, or other types of DNA damage.
Mutations can also occur as a result of mobile genetic elements inserting or deleting portions of DNA.
Examples of Mutations
A single nucleotide change can result from a point mutation, as in sickle cell anemia, when a single nucleotide change in the gene of the beta-globin chain results in a change in amino acid in the polypeptide chain.