Positive growth regulator mutations that cause hyperactivity are often genetically dominant, which means that even when a normal gene is present on the homologous chromosome, a mutant gene on one chromosome can promote the growth of tumors.
These genes are sometimes referred to as oncogenes, and their normal forms are referred to as proto-oncogenes.
proto-oncogenes are the genes involved in normal cell growth.
Oncogenes are the mutant, cancer-promoting forms of these genes.