A frameshift mutation is a genetic change brought on by an insertion or deletion that changes how the DNA sequence is read.
A chain of numerous smaller molecules known as nucleotides makes up a DNA sequence.
Cystic fibrosis is brought on by two frameshift mutations in the CFTR genes (one involves the insertion of two nucleotides, and the other involves the deletion of one nucleotide).
Deletion frameshift mutation: When in the nucleic acid, one or more nucleotides are deleted, resulting in reading frameshift.
Insertion frameshift mutation: When in the nucleic acid, one or more nucleotides are added, resulting in reading frameshift.