Question

What are the functions of the follicles during oogenesis?

Answer 1

Role of the follicles:

1. The follicle is important in the ovary's twin function of oocyte maturation and release, as well as steroidogenesis, which is essential for the ovary to regulate its own development and provide the right environment in reproductive organs for gamete transit and nidation.
2. Follicle cells create an epithelial to protect the germline cells underneath.
3. Follicle cells undergo shape changes and morphogenetic motions as oogenesis progresses, finally giving rise to the intricate structure of the eggshell.
4. Normal folliculogenesis necessitates the expression of a group of early expressed genes.
5. The recruitment of theca cells from cortical stromal cells is stimulated by granulosa cell components.
6. Granulosa cell growth is aided by thecal factors, which also decrease granulosa cell death.
7. The synthesis of growth factors in the various follicular compartments is influenced by cell-cell and cell-extracellular matrix interactions.
8. Several autocrine and paracrine factors have a role in follicular development and differentiation.