Question

What are the main modes of inheritance?

Answer 1

Inheritance

1. For single-gene illnesses, there are four primary inheritance modes: autosomal dominant, autosomal recessive, X-linked dominant, and X-linked recessive.
2. However, these patterns do not apply to all genetic disorders, and other unusual kinds of inheritance, such as mitochondrial inheritance, do exist.
3. Autosomal Dominant: each affected person usually has a parent who is also affected; it occurs in every generation.
4. Autosomal Recessive: both parents of a person who is affected are carriers; not observed in every generation.
5. Dominant X- chromosome females are more commonly impacted because an afflicted man's daughters and no boys will be affected; if the mother is affected, affected males and females in the same generation will be affected.
6. Males are more commonly afflicted by X-linked recessive mutations; affected males are often present in each generation.