Question

What Are The Stages Of Translation?

Answer 1

Translation:

1. The translation is the last step in the Central Dogma proposed by Francis Crick.
2. It is the process of formation of a primary polypeptide chain expressing respective codons present in mRNA.
3. The transfer or t-RNA carries the mRNA chain to the ribosome where the RNA sequence is translated to an amino acid sequence.
4. Once the amino acid chain is synthesized, it undergoes multiple folding to form a functional protein.

The three steps of translation are:

1. Activation or charging of tRNAInitiation – recognition of start codon(AUG) binding of ribosomal subunits to mRNA and formation of initiation complex with Methionine-tRNA entering from the A site and binding at the P site.
2. Elongation – peptide bond formation and growing of polypeptide chains by addition of amino acids bound to their respective tRNA.
3. Termination – stop codon (UAA, UAG, UGA) enters the A site, resulting in the termination of the process.