Question

What are the three post transcriptional modifications?

Answer 1

Post-transcriptional modification:

1. RNA is formed from DNA by the process of transcription.
2. The step involved in protein biosynthesis is a post-translational modification (PTM).
3. There is the generation of proteins when polypeptide chains are formed from the ribosomes' mRNA.

The three post-transcriptional modifications are as follows:

1. Splicing: This involves the removal of the part of the gene that does not code for any protein (introns) and joining all the coding genes (exons) to form a functional gene.
2. Capping: This involves the addition of nucleotide methylguanosine triphosphate to the 5'-phosphate end of the mRNA. It guides the mRNA safely to the cytoplasm upon its exit from the nucleus.
3. Tailing: This involves the addition of poly-adenosine residues to the 3'-end of the mRNA.