Variation refers to differences between individuals or to differences between populations. Mutation is the ultimate source of genetic variation, but mechanisms such as sexual reproduction and gene flow contribute to it as well.
A mutation is a change in the DNA sequence. These variations in gene sequences can sometimes be advantageous to an organism. Most mutations that result in genetic variation produce traits that confer neither an advantage or disadvantage.
Gene flow introduces new genes into a population as organisms migrate into a new environment. New gene combinations are made possible by the availability of new alleles in the gene pool.
Sexual reproduction promotes genetic variation by producing different gene combinations. Meiosis is the process by which sex cells or gametes are created. Genetic variation occurs as alleles in gametes are separated and randomly united upon fertilization. The genetic recombination of genes also occurs during crossing over of gene segments in homologous chromosomes during meiosis.