Question

What can excess manganese induce?

Answer 1

Manganese toxicity:

1. Excess of manganese in body induces deficiencies of iron, magnesium & calcium.
2. Manganese toxicity results in permanent neurological disorder known as manganism.

Symptoms of manganism:

1. Neurological tremors
2. Difficulty in walking
3. Facial muscle spasms.
4. Irritability, aggressiveness, and even hallucinations.

Treatment of manganism:

1. The chelation therapy has also been used for the treatment of severe cases of manganese intoxication.
2. EDTA treatment has been shown to increase the manganese excretion in urine & decrease manganese concentrations in the blood.
3. Clinical symptoms do not appear to be significantly improved among patients.