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Question

What causes the right shift in the oxyhemoglobin dissociation curve?


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Solution

Dissociation curve:

  1. The dissociative curve is the saturation of oxyhemoglobin percentage at different oxygen partial pressures.
  2. The curve gives the equilibrium of hemoglobin and oxyhemoglobin at different partial pressures.
  3. The oxygen partial pressure is high in the lungs where oxyhemoglobin is formed by the binding of hemoglobin with oxygen.
  4. The oxygen partial pressure is low in the tissues where hemoglobin is formed by the release of oxygen from oxyhemoglobin.

Cause for the right shift:

  1. The right shift in the oxygen dissociation curve is due to an increase in partial pressure of carbon dioxide or a decrease in the pH.
  2. At the high partial pressure of carbon dioxide, hydrogen ions concentration and temperature favor dissociation of oxygen from oxyhemoglobin and show the reduced affinity of hemoglobin for oxygen.
Effect pH on oxygen dissociation curve

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