Angiogenesis: It is defined as the formation of new blood vessels or capillaries from pre-existing vasculature by migration and proliferation of endothelial cells.
The factor that Angiogenesis could result from-
Angiogenesis occurs in some normal physiological events.
Angiogenesis is a normal and vital process in growth and development, as well as in wound healing and menstruation.
In tumors, angiogenesis results in the growth, invasion, and spread of cancer cells.
Examples of angiogenesis inhibitors that are approved to treat cancer are Axitinib (Inlyta) which is approved to treat Kidney cancer and Sunitinib (Sutent) which is approved to treat gastrointestinal stromal tumors (GIST), Kidney cancer.