Question

What diseases can be determined by biochemical methods?

Answer 1

Biochemical methods: These methods are used to diagnose hereditary metabolic exchange diseases and are determined at three levels:

1. Molecular (examination of protein structure and amount)
2. Cellular (evaluation of defective enzymes)
3. Organismal (searching for intermediate metabolites)

Biochemical methods can be used to diagnose the following diseases:

1. Hemoglobinopathy,
2. Amino acid exchange failure (phenylketonuria, alkaptonuria)
3. Carbohydrate-substrate diseases (diabetes mellitus, galactosemia, fructoseuria)
4. Lipid-substrate diseases (hypercholesterolemia, amaurotic idiocy)
5. Mineral-substrate diseases (Hemochromatosis, Konovalov-Wilson illness)