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B
Its sequence of amino acids
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C
Its three-dimensional shape
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D
Its peptide bonds
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Solution
The correct option is A Its three-dimensional shape Protein which is affected by high temperature gets denatured which loses its three-dimensional structure and adverse its functions by changing its shapes. The primary structure or the sequence of amino acids are bonded by peptide bonds which do not get easily broken but the other bonds such as hydrogen bonds, disulphide bonds, etc get denatured thus affecting its shape and function.
Hence, the correct answer is 'Its three-dimensional shape'.