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Question

What does falling progesterone in the secretary endometrium cause?


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Solution

Falling progesterone in the secretary endometrium:

  1. The falling progesterone in the secretory endometrium produces the tissue locally producing prostaglandin.
  2. Prostaglandin causes vascular spasms of the spiral arterioles and resultant ischemia and sloughing of the endometrium.
  3. This is the experience of ‘periods’ by women ages 13-45.
  4. The uterine cramping linked with the normal ovulatory cycle is a result of the activity of prostaglandin.
  5. It describes the effectiveness of prostaglandin inhibitors in treating dysmenorrhea.

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