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Question

What enzyme is used to catalyze the first primary reaction of glycolysis?

A
Hexokinase
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B
Enolase
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C
Phosphofructokinase-1
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D
Pyruvate kinase
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Solution

The correct option is A Hexokinase
Glycolysis is an oxygen independent metabolic pathway that converts glucose, into pyruvate.
This process of conversion can be divided into two stages, a preparatory stage and a pay-off stage.
The intial five steps of glycolysis are known as the preparatory stage. During these steps there is ​​​​​​consumption of ATP and is also known as the investment stage.
The remianing steps of glycolysis are known as the pay-off phase of glycolysis. This phase is characterized by gain of the energy-rich molecules ATP and NADH.
The first step in the preparatory stage of glycolysis is phosphorylation. During this step, glucose is phosphorylated to glucose-6-phosphate by the enzyme hexokinases with the consumption of an ATP molecule.

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